Zhenguan Technology — Aseptic Pharmaceutical Equipment Manufacturer

Zhenguan Technology (臻灌科技) is a technology-driven enterprise specializing in R&D, production, sales, and service of pharmaceutical filling and packaging equipment. Our team has over 10 years of experience in small-volume injectable filling systems, with deep expertise in prefilled syringe filling lines, catheter flush syringe fillers, and rod labeling machines. We provide customized, turnkey solutions to leading pharmaceutical and biotech companies including Bloomage Biotech, CSPC, FREDA Pharma, Amoytop Bio, and Minhai Biotech.

Our Mission & Vision

Mission: To create value for customers through advanced technology and professional service, driving high-quality development in the pharmaceutical industry.

Vision: To become the preferred prefilled syringe total-solution expert in the pharmaceutical sector, empowering safe medication with precise and reliable equipment.

Team Edge: Our engineers combine German engineering expertise with extensive project experience at major pharmaceutical companies, focusing on innovation and detail optimization to continuously upgrade industry equipment technology.

Main Products / 主要产品

1. Prefilled Syringe Vacuum Filling & Stoppering Machine — PFVS-2Y (2-head)

Applications: High-viscosity products, hyaluronic acid, collagen, plant proteins, chitosan, hydroxyapatite, gels, cross-linked products, and microsphere-containing formulations.

Technical Highlights: Sleeve-free stoppering (eliminates deformation & particulate contamination); independent vacuum circuit with analog monitoring; real-time vacuum pressure traceability (GMP-compliant); 100% bubble-free filling; non-contact filling needle; collision protection.
Key Parameters: 2 filling/stoppering heads; ceramic/stainless steel piston pump; syringe sizes 1–20 mL; filling accuracy ±1%; capacity 4,200 pcs/h (mechanical) / 1,600 pcs/h (vacuum); vacuum range 0–50 kPa; stoppering yield ≥99.9%; power 14 kW; dimensions 2050×950×2600 mm.

2. Prefilled Syringe Vacuum Filling & Stoppering Machine — PFVS-5Y (5-head)

Applications: Same as PFVS-2Y, but for higher throughput.

Technical Highlights: Same advanced features as PFVS-2Y (sleeve-free, independent vacuum, analog monitoring, modular design, etc.), with 5 synchronized heads for higher efficiency.
Key Parameters: 5 heads; capacity 11,000 pcs/h (mechanical) / 4,500 pcs/h (vacuum); power 22 kW; dimensions 1900×1550×2600 mm; weight 2,700 kg.

3. Complete Filling Line — PFVS-5Y-LINE

Full turnkey production line integrating bag cutting, inner liner removal, and vacuum filling & stoppering. Designed for challenging formulations (biologics, gels, cross-linked products).

Advantages: 5-head synchronous filling for high consistency; vacuum environment for bubble-free filling; yield ≥99.9%; fully customizable.
Key Parameters: 5 heads; capacity 11,000 pcs/h (mechanical) / 4,500 pcs/h (vacuum); power 27 kW; dimensions 4250×2200×2500 mm.

4. Prefilled Catheter Flush Syringe Filling Machine — PFCH-F6 (6-head)

Applications: Medical saline, alcohol, sodium chloride solutions, gels, and other flush syringe products.

Technical Highlights: Fully automatic (feeding, silicone oil spraying, ionized air cleaning, cap tightening, filling, stoppering, reject handling); optional Grade A laminar flow; drip-back suction; 360° ionized air cleaning; in-line vision inspection (liquid level, stopper presence, cap presence); precise servo-controlled torque capping.
Key Parameters: 6 heads (or multi-head); ceramic pump; capacity 13,000 pcs/h (mechanical); filling accuracy ±1%; capping yield ≥99.9%; power 19 kW; dimensions 5000×2000×2600 mm; weight 6,500 kg.

5. Rod Labeling Machine — SLM-200

Applications: Capping and labeling for prefilled syringes (biologics, aesthetic products, vaccines, small-volume injections).

Technical Highlights: Single operator; high-capacity plunger hopper; anti-breakage protection; excellent concentricity; full servo torque control; online vision inspection (plunger height, label presence, code presence).
Key Parameters: Suitable for 0.5–20 mL plastic/glass syringes; labeling speed 300 pcs/min; labeling accuracy ±0.5 mm; label size (L)15–100×(W)10–80 mm; yield ≥99.9%; power 380V 50Hz; weight 1,500 kg; dimensions 4055×1310×1900 mm.

6. Catheter Flush Syringe Complete Production Line — PFCH-F6-LINE

Full automated line covering sorting, feeding, silicone oil spraying, ion cleaning, capping, filling, stoppering, reject removal, tray loading, nest separation, visual inspection, rod labeling, and packaging.

Advantages: Wide compatibility; optional automatic replenishment; Grade A laminar flow; drip-back suction; 360° ionized cleaning; in-line vision inspection; fully customizable.
Key Parameters: Capacity 12,000 pcs/h (mechanical); power 380V 50Hz.

Core Technology / 核心技术

Sleeve-free direct compression stoppering — Eliminates stopper deformation and particulate shedding, ensuring sealing integrity and 100% bubble-free performance.
Independent servo-controlled filling station — Each needle individually adjustable with suck-back function to prevent dripping; collision protection.
High-sensitivity analog vacuum monitoring — Real-time continuous measurement for consistent batch-to-batch vacuum levels, fully GMP traceable.
Modular design — Simplifies format changeover and reduces maintenance downtime.
Non-contact filling — Prevents contamination and splashing.
316L stainless steel central disc clamping — X/Y high-precision servo axes ensure syringe stability and needle alignment.
Honeycomb plate pick-and-place system — For sterile retrieval of RTU syringes from Nest & Tub trays under Grade A conditions.
Siemens industrial touch control — Centralized parameter control, recipe management, alarm logging, and full data traceability.

After-Sales Service / 售后服务

Rapid Response: Remote diagnosis + on-site engineer support to minimize downtime.
Spare Parts & Maintenance: Genuine parts supply, preventive maintenance plans, and regular equipment health checks.
Installation & Commissioning: Full documentation (DQ/IQ/OQ/PQ, FAT/SAT) and process parameter optimization.
Process Upgrades: Adaptation for new product specifications, filling accuracy improvement, format changeover efficiency enhancement, and automation upgrades throughout the equipment lifecycle.

臻灌科技 — 无菌制药装备制造商

臻灌（浙江）科技有限公司 是一家以制药灌装设备、包装设备等非标设备的研发、生产、销售和服务为一体的科技型企业。团队专注小容量注射剂灌装设备研发制造，拥有10余年行业经验，依托德国工程技术，为华熙生物、石药集团、福瑞达医药、特宝生物、民海生物等知名药企提供定制化解决方案。

使命与愿景

使命：以先进技术与专业服务为客户创造价值，推动行业高质量发展。
愿景：成为制药行业首选预灌封整体解决方案专家，赋能安全用药。

主要产品

预灌封真空灌装加塞机 PFVS-2Y（2头） — 适用高粘产品（玻尿酸、胶原蛋白、凝胶等），无套筒真空加塞，独立真空回路，100%无气泡，精度±1%，产能4200支/小时（机械）/1600支/小时（真空）。
预灌封真空灌装加塞机 PFVS-5Y（5头） — 5头同步，产能11000支/小时（机械）/4500支/小时（真空），功率22kW。
五头机整线 PFVS-5Y-LINE — 全自动无菌生产线（开袋、去内纸、真空灌装加塞），产能11000支/小时。
预充式导管冲洗器高速灌装机 PFCH-F6（6头） — 适用于生理盐水、酒精、凝胶等，全自动喷硅油、离子风清洗、伺服拧帽、在线视觉检测，产能13000支/小时，精度±1%。
拧杆贴标机 SLM-200 — 预灌封注射器拧杆贴标，精度±0.5mm，速度300支/分钟，具备防撞保护、扭矩控制、视觉检测。
冲洗器高速灌装整线 PFCH-F6-LINE — 全自动整线（理料、灌装、加塞、装盘、灯检、拧杆贴标、包装），产能12000支/小时。

核心技术优势

无套筒直压加塞 — 杜绝胶塞变形与微粒污染，确保密封与100%无气泡。
独立伺服灌装 — 每针独立调节，具备回吸防滴漏、防撞保护。
高精度模拟量真空监测 — 实时在线，数据可追溯，符合GMP要求。
模块化设计 — 快速换型，维护便捷。
非接触灌装 — 防止污染与飞溅。
316L不锈钢中心盘 + X/Y高精度伺服 — 保证针管稳定与对中。
蜂窝板取料系统 — RTU注射器无菌转运（A级环境）。
西门子触控系统 — 集中控制、配方管理、报警记录、数据存储。

售后服务

快速响应：远程诊断 + 现场支持，最大程度降低停机。
备件与维护：原厂备件供应，预防性维护，定期设备巡检。
安装调试：提供DQ/IQ/OQ/PQ、FAT/SAT等全套文档及工艺优化。
工艺升级：支持新规格适配、精度优化、换型效率提升、自动化升级等全生命周期服务。

Zhenguan Technology (Zhejiang) Co., Ltd.
Address: Room 101, 4th Floor, Building 3, No. 501 Changsheng South Road, Jiaxing, Zhejiang, China
Tel: +86 13671748040 ｜ +1 (773) 349-0224
Email: sales@zhenguankeji.com ｜ Website: www.zhenguankeji.com

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